To learn more about our innovative technology and bypassing the blood-brain barrier, we recommend reading the following published articles:
Dhuria SV, Hanson LR, Frey WH 2nd. Intranasal Delivery to the Central Nervous System: Mechanisms and Experimental Considerations. J Pharm Sci. April 2010; Volume 99(4):1654-73. PubMed: 19877171
Hoekman JD and Ho RJY. Brain Effects of Localized Hydrophilic Mannitol and Hydrophobic Nelfinavir Administration Targeted to Olfactory Epithelium on Brain Distribution. AAPS PharmSciTech. June 2011 Volume 11(2):534-43. PubMed: 21519984
Hoekman JD and Ho RJY. Enhanced Analgesic Responses Following Preferential Delivery of Morphine and Fentanyl to the Olfactory Epithelium. Anesthesia and Analgesia. Sept 2011 Volume 113(3): 641-51. PubMed: 21709146
Lochhead JJ, Thorne RG. Intranasal Delivery of Biologics to the Central Nervous System. Adv Drug Deliv Rev. 2011 Nov 15. PubMed: 22119441
